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Interleukin 12 cellular and molecular immunology of an important regulatory cytokine by

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Published by New York Academy of Sciences in New York, N.Y .
Written in English


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Book details:

Edition Notes

Other titlesInterleukin twelve
Statementedited by Michael T. Lotze ... [et al.].
SeriesAnnals of the New York Academy of Sciences,, v. 795
ContributionsLotze, Michael T., New York Academy of Sciences., Genetics Institute, Inc.
LC ClassificationsQ11 .N5 vol. 795, QR185.8 .N5 vol. 795
The Physical Object
Paginationxix, 457 p. :
Number of Pages457
ID Numbers
Open LibraryOL997305M
ISBN 101573310182, 1573310190
LC Control Number96036006

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Interleukin Cellular and Molecular Immunology of an Important Regulatory Cytokine (Annals of the New York Academy of Sciences) Hardcover – November 1, by Michael T. Lotze (Editor), Giorgio Trinchiere (Editor), Maurice Gately (Editor), Stanley Wolf (Editor) & 1 moreFormat: Hardcover. Interleukin (IL) Monocytes produce IL Its principal targets are T cells. It causes induction of Th1 cells. Besides, it is a potent inducer of interferon gamma production by T lymphocytes and NK cells. Interleukin (IL) CD4+T cells (Th2), NKT cells and mast cells synthesize IL Recombinant Mouse Interleukin, 2UG by TSZGENE. Interleukin Interleukin (IL) plays an integral role in the ability of the innate and adaptive immune systems to communicate and work together. Specifically, it plays a role in the production of Th1 CD4+ helper T cells. 12 The effector T cells then assist in the promotion of the cell-mediated cytotoxic activity of CD8+ and NK cells.

  The interleukin 12 (IL)/IL common pathway has been found to play a determinant role in the induction of inflammation in adaptive immune responses. In particular, IL promotes the differentiation of naïve T helper cells into Th17 phenotype with the concomitant secretion of several inflammatory cytokines such as IL and IL, whereas Cited by: 3.   Interleukin 12 (IL) is a pleiotropic cytokine, the actions of which create an interconnection between the innate and adaptive immunity. IL was first described as a factor secreted from PMA-induced EBV-transformed B-cell by: recombinant interleukin A recombinant form of the endogenous heterodimeric cytokine interleukin with potential antineoplastic activity. Recombinant interleukin binds to and activates its cell-surface receptor, stimulating the production of interferon-gamma (IFN) which, in turn, induces IFN-gamma-inducible protein (IP) and so inhibits tumor angiogenesis. HemaMax™, a Recombinant Human Interleukin, Is a Potent Mitigator of Acute Radiation Injury in Mice and Non-Human Primates Lena A. Basile,1,*Dolph Ellefson,1Zoya Gluzman-Poltorak,1Katiana Junes-Gill,1Vernon Mar,1Sarita Mendonca,1Joseph D. Miller,2Jamie Tom,1Alice Trinh,1and Timothy K. Gallaher1Cited by:

Interleukin (IL) was described by Trinchieri () and it was subsequently disclosed to be produced by B cells, monocytes and other accessory cells (Trinchieri and Scott, ). Discover the best Interleukin 12 books and audiobooks. Learn from Interleukin 12 experts like Frontiers and Frontiers. Read Interleukin 12 books like and tmptmp for free with a free day trial. This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Interleukin 12 (IL) is an interleukin that is naturally produced by dendritic cells, macrophages, neutrophils, and human B-lymphoblastoid cells in response to antigenic belongs to the family of interleukin IL family is unique in comprising the only heterodimeric cytokines, which includes IL, IL, IL and IL PDB: 1F